T2-mapping in normal volunteers compared to patients with edema reveals wide range of myocardial T2 in female volunteers

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T2-mapping in normal volunteers compared to patients with edema reveals wide range of myocardial T2 in female volunteers

Methods We scanned 72 healthy volunteers (36±13 years, 18 females, heart rate 71±10 bpm) in a 1.5 T scanner. All had no cardiac disease and no signs of inflammation. We applied a FLASH and a SSFP-based T2-mapping sequence resulting in 3 single-shot images with echo times of 0, 24 and 54 ms and a pixel size of 2.7 x 2.1 mm (slice thickness 8 mm). Images were obtained in midventricular short axis...

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Variability and homogeneity of cardiovascular magnetic resonance myocardial T2-mapping in volunteers compared to patients with edema

BACKGROUND The aim of the study was to test the reproducibility and variability of myocardial T2 mapping in relation to sequence type and spatial orientation in a large group of healthy volunteers. For control T2 mapping was also applied in patients with true edema. Cardiovascular magnetic resonance (CMR) T2-mapping has potential for the detection and quantification of myocardial edema. Clinica...

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Myocardial T2 mapping reveals age- and sex-related differences in volunteers

BACKGROUND T2 mapping indicates to be a sensitive method for detection of tissue oedema hidden beyond the detection limits of T2-weighted Cardiovascular Magnetic Resonance (CMR). However, due to variability of baseline T2 values in volunteers, reference values need to be defined. Therefore, the aim of the study was to investigate the effects of age and sex on quantitative T2 mapping with a turb...

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T2 mapping for the detection of myocardial edema in patients with acute myocarditis

Background In patients with acute myocarditis, T2-weighted cardiovascular magnetic resonance (CMR) can visualize myocardial edema and is used for one of the three recommended diagnostic CMR criteria. There are, however, significant technical problems associated with the short-tau-inversion-recovery (STIR) sequence, limiting its clinical utility. Quantitative T2 mapping technique may overcome su...

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Cardiovascular magnetic resonance T2 mapping detects myocardial edema in patients with chronic dilated cardiomyopathy

Background Global myocardial edema, a surrogate measure of myocardial inflammation, has been reported in patients with chronic dilated cardiomyopathy (DCM) based on T2weighted STIR imaging. However, STIR imaging is prone to motion artefact and issues related to cardiac cycle timing and coil sensitivity. We hypothesised that a novel quantitative CMR T2 mapping technique would provide a reliable ...

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ژورنال

عنوان ژورنال: Journal of Cardiovascular Magnetic Resonance

سال: 2012

ISSN: 1532-429X

DOI: 10.1186/1532-429x-14-s1-o81